Filgrastim nursing interventions

Nursing Considerations. • May cause seizures, tremors, hypertension, hepatotoxicity, diarrhea, N/V, gingival hyperplasia. • Increases immune suppression with corticosteroids. • Avoid grapefruit juice while taking this medications. • Assess for signs of organ rejection. • Monitor renal panel, liver enzymes. • Take medication as directed.

Filgrastim nursing interventions. Study with Quizlet and memorize flashcards containing terms like A nursing assistant in a nursing home reports to the nurse that an 87-year-old nursing home client has a 6-inch reddened wound with pus draining from it on his shin where he scratched it open yesterday. After directly assessing the client's wound, what are the most relevant priority actions for the nurse to take? Select all that ...

Given that filgrastim has common side-effects (including bone pain, headaches, fever, joint and muscle pains as well as injection site pain), requires daily subcutaneous administration, and is expensive (about Can$192/dose for Neupogen and Can$144/dose for Grastofil), identification of its optimal duration is an important clinical …

Approach Considerations. Medical care for patients with neutropenia is mostly supportive and is based on the etiology, severity, and duration of the neutropenia. Fever and infections occurring as complications of neutropenia require specific treatment; see Antimicrobial Agents in Neutropenic Cancer Patients. Surgical care is not usually ...Filgrastim is a medication used to manage and treat neutropenia in patients with myelosuppression from chemotherapy or radiation, which increases the risk of infection and related events. This activity outlines the indications, actions, contraindication, adverse effects, and other important details of filgrastim as it pertains to members of the ...Given that filgrastim has common side-effects (including bone pain, headaches, fever, joint and muscle pains as well as injection site pain), requires daily subcutaneous administration, and is expensive (about Can$192/dose for Neupogen and Can$144/dose for Grastofil), identification of its optimal duration is an important clinical …aka. neupogen. class. increase neutrophil production, colony-stimulating factor. actions. increase neutrophil production in bone marrow and enhance phagocytoic and cytotoxic function of existing neutrophils. who does it help. pt. with neutropenia assoc. w/ bacterial and fungal infections. who gets it.When you're asked questions – either on an application or in an interview – for a nursing scholarship, be ready with meaningful answers. Try to learn why the grantor is giving scho...

This information will teach you how to give yourself a subcutaneous (SUB-kyoo-TAY-nee-us) injection (shot) with filgrastim (Neupogen) or pegfilgrastim (Neulasta) using a prefilled syringe. A subcutaneous injection is an injection that is given under your skin.The biologic response modifiers are a group of drugs that can either extend the immune system’s ability to rid the body of damaging attackers or help the immune system to function normally. This group is composed of the interferons, interleukins, hematopoietic agents, and colony-stimulating factors. They are mainly used in the …This information will teach you how to give yourself a subcutaneous (SUB-kyoo-TAY-nee-us) injection (shot) with filgrastim (Neupogen) or pegfilgrastim (Neulasta) using a prefilled syringe. A subcutaneous injection is an injection that is given under your skin.The nursing process functions as a systematic guide to client-centered care with 5 sequential steps. These are assessment, diagnosis, planning, implementation, and evaluation. Assessment. Assessment is the first step and involves critical thinking skills and data collection; subjective and objective. Subjective data involves verbal statements ...Heparin is a commonly used medication in various healthcare settings, primarily to prevent and treat blood clots. As a nurse, it is essential to perform a comprehensive nursing assessment before administering heparin to ensure safe and effective patient care. 1. Review patient’s medical history.A nurse practitioner (NP) is a nurse with a graduate degree in advanced practice nursing. This type of provider may also be referred to as an ARNP (Advanced Registered Nurse Practi...Study with Quizlet and memorize flashcards containing terms like Which action will the admitting nurse include in the care plan for a patient who has neutropenia? a. Avoid intramuscular injections. b. Check temperature every 4 hours. c. Omit fruits or vegetables from the diet. d. Place a "No Visitors" sign on the door., Which laboratory test will the …

Put the original carton with any unused prefilled syringes back in the refrigerator. Remove the syringe tray from the carton. On a clean, well-lit surface, place the syringe tray at room temperature for 30 minutes before you give an injection. Do not use the prefilled syringe if the carton is damaged.Mar 24, 2009 · The most reliable, and often the only, sign is fever. Teach patients to monitor their temperature and seek medical attention immediately for temperatures of 100.4º F (38º C) or higher. Neutropenic fever, usually defined as a single temperature greater than 100.4º F and an ANC of less than 500/mm3, is a medical emergency. Nursing Interventions. Client Education. Matilda Hjaertstroem Filgrastim Therapy 26 Leukopoietic Growth Factors. Leukopoietic growth factors stimulate the bone marrow to increase production of neutrophils. IVboluss continous IVs subcutaneous infusions subcutaneous injection. calculated bymcm/km; IVinfusion ovr 15 -30 min; Duration of …When you're asked questions – either on an application or in an interview – for a nursing scholarship, be ready with meaningful answers. Try to learn why the grantor is giving scho...

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In health-care professions, “therapeutic use of self” describes the ability of a caregiver to use his or her personality “consciously and in full awareness in an attempt to establi...Drug: Filgrastim. Injection of ZARZIO 30 MU/0,5mL and/or ZARZIO 48 MU/0,5mL, over a period of 5 consecutive days (1 injection per day during 30 minutes - - day 1 : set up standard treatment). The filgrastim solution will be diluted in 20 mL of 5% Glucose. The dose of ZARZIO administrated depends of the patient's weight :Approximately 9% of patients receiving allogeneic HCT will develop a CLABSI. 28,29 Evidence suggests that the most common organism causing a CLABSI is Staphylococcus epidermidis, a bacterium naturally found on the skin. 29 Nursing interventions to prevent CLABSI include performing a sterile dressing change if found …aka. neupogen. class. increase neutrophil production, colony-stimulating factor. actions. increase neutrophil production in bone marrow and enhance phagocytoic and cytotoxic function of existing neutrophils. who does it help. pt. with neutropenia assoc. w/ bacterial and fungal infections. who gets it.

It is given as a shot into the fatty part of the skin on the top of the thigh or the belly area. This drug may be given into the buttocks or the outer area of the upper arm if given by someone else. Some products may be given as an infusion into a vein over a period of time. Talk with the doctor if you have questions.Neupogen (Filgrastim Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. ... Seek …Study with Quizlet and memorize flashcards containing terms like A patient receiving filgrastim therapy complains of bone pain. What will the nurse do first? A) hold the medication B) call the health care provider C) administer the ordered nonopioid analgesic D) increase the dose of filgrastim, The nurse is caring for a patient who is being treated …Vitamin B 12 Deficiency Adult: IM/Deep SC 30 mcg/d for 5–10 d, then 100–200 mcg/mo Child: IM/Deep SC 100 mcg doses to a total of 1–5 mg over 2 wk, then 60 mcg/mo Pernicious Anemia Adult: IM/Deep SC 100–1000 mcg/d for 2–3 wk, then 100–1000 mcg q2–4wk Intranasal one pump in one nostril once weekly Child: IM 30–50 mcg/d times 2 …When you're asked questions – either on an application or in an interview – for a nursing scholarship, be ready with meaningful answers. Try to learn why the grantor is giving scho...Diagnosis of Neutropenia. Along with the signs and symptoms, neutropenia is primarily diagnosed by obtaining a blood sample from the patient. The normal neutrophil count is above 2.0 and less than 7.5. The following are the types of neutropenia: Mild Neutropenia: 1.0- to 2.0. Moderate Neutropenia: 0.5 to 2.0.What are the Indications for FILGRASTIM? 1 INDICATIONS AND USAGE RELEUKO is a leukocyte growth factor indicated to: Decrease the incidence of infection‚Äö as …Drug Name Generic Name : ritonavir Brand Name: Norvir Classification: Antiretroviral Pregnancy Category B Dosage & Route Available forms :Capsules—100 mg; oral solution—80 mg/mL ADULTS 600 mg PO bid with food. PEDIATRIC PATIENTS Start at 250 mg/m2 PO bid and increase by 50 mg/m2 twice daily at 2–3 day intervals, to maximum of …Chemotherapy Nursing Interventions: Rationale: 1. Ask the patient about the rate of his or her fatigue using the numeric scale and ask the time of day when it is most severe. Assessing the rate of fatigue will help the nurse in developing a plan of care for managing the patient’s fatigue. 2.Oct 20, 2022 · A. Filgrastim is a medication that is given to cancer patients to stimulate the growth of the white blood cells in order to make the patients less vulnerable to diseases. It increases the production of neutrophils in the bone marrow. The following nursing interventions are appropriate to safely administer filgrastim and provide patient safety ... Interventions For patients who are medically able to begin exercise, implement appropriate resistive exercises and aerobic training to maintain muscle strength and aerobic capacity during cancer chemotherapy or to help restore function after chemotherapy.

Nursing Interventions. Client Education. anna vanasselberg filgrastim (Neupogren) PHARM Cht leukopoietic growth factor. binds to and stimulates immature neutrophils to divide and differentiate. also activates mature neutrophils. filgrastim interferes with the action of cytotoxic drugs. lithium potentiates release of neutrophils. leukocytosis ...CLASS: beta blockers. -ACTION: blocks stimulation of beta1 (myocardial)-adrenergic receptors; Decreased BP, HR, frequency of CP attacks, and rate of cardiovascular deaths. -SIDE EFFECTS: fatigue, weakness, BRADYCARDIA, HF, PULMONARY EDEMA, erectile dysfunction. -Monitor BP, ECG, and pulse frequently; Monitor I&O ratios and daily …Subcutaneous. Do not administer filgrastim in the period 14 d before or 24 h after cytotoxic chemotherapy. Use only one dose per vial; do not reenter the vial. Prior to injection, …Find information on Filgrastim (Granix, Neupogen) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.LANCASTER, Pa., April 29, 2020 /PRNewswire-PRWeb/ -- The travel nurse industry is stepping up to fill the desperate need for nurses during the COV... LANCASTER, Pa., April 29, 2020...Infections, other health conditions and exposure to chemicals can also lead to severely low neutrophil levels. Causes of acquired agranulocytosis include: Autoimmune diseases, including lupus and rheumatoid arthritis. Bone marrow disease and bone marrow failure disorders like aplastic anemia. Cancers that affect your bone …Nursing Interventions Client Education Jamie Heil Filgrastim 32 Colony-stimulating factor increase neutrophil production in bone marrow and enhance the phagocytic and cytotoxic function of existing neutrophils IV-continuous infusion Subcutaneous Filgrastim not administered until at least 24hrs after chemotherapy because antineoplastic drugs and ...May 2, 2023 · hair loss, headache, tired feeling, skin rash, nosebleeds, or. injection site reactions (redness, swelling, itching, lumps or bruising). Tell your doctor if you have rare but very serious side effects of Neupogen including: easy bleeding or bruising, bloody urine, Dec 3, 2019 · Pegfilgrastim (or biosimilar) is administered 24 to 72 hours after the last dose of myelosuppressive chemotherapy during each of the 8 intensive treatment courses. If patients are unable to receive the long-acting pegfilgrastim product, daily filgrastim (or biosimilar) can be administered until the absolute neutrophil count is >1000 cells/mm 3 ...

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Nursing Care Plan for Chemotherapy 3. Risk for Infection. Nursing Diagnosis: Risk for Infection related to inadequate secondary defenses, immunosuppression secondary to chemotherapy for skin cancer. Desired Outcomes: The patient will remain free from infection and will be able to achieve timely healing as appropriate.GRANIX (tbo-filgrastim) is a leukocyte growth factor indicated in adult and pediatric patients 1 month and older for reduction in the duration of severe neutropenia in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia. ( 1 )Granulocyte colony-stimulating factor (G-CSF)—filgrastim, filgrastim-sndz, tbo-filgrastim, or pegfilgrastim—is indicated for the prevention of chemotherapy-induced neutropenia in patients ...Approach Considerations. Medical care for patients with neutropenia is mostly supportive and is based on the etiology, severity, and duration of the neutropenia. Fever and infections occurring as complications of neutropenia require specific treatment; see Antimicrobial Agents in Neutropenic Cancer Patients. Surgical care is not usually ... Therefore, options 1, 2, and 3 are safe nursing interventions since this client is experiencing hypernatremia due to excess sodium. Option 4 would be an unsafe nursing action that could further exacerbate the condition. If the nurse noted this in the treatment plan, the nurse would contact the primary health care provider for further clarification. More interventions for pain at Acute Pain Nursing Care Plan. 5. Reducing Anxiety. Postpartum hemorrhage is one of the most severe obstetric complications contributing to maternal morbidity and mortality. A postpartum hemorrhage can be a dramatic, life-threatening event and may occur in the context of extreme pain or obstetric …Considering these new recommendations during the pandemic and the general trend toward value-based care in oncology, we compared the different CSF prophylaxis strategies from a clinical and economic perspective by assessing the cost-effectiveness of PP versus SP using a biosimilar filgrastim (specifically filgrastim-sndz) in patients with ...Quy hoạch giao thông xã Phú Cát được xác định theo sơ đồ định hướng phát triển giao thông của bản đồ quy hoạch chung xây dựng huyện Quốc Oai đến năm …Filgrastim is a man-made version of G-CSF that stimulates white blood cell production, and in particular, neutrophil production. A neutrophil is a type of white blood cell that is responsible for fighting infection and is often decreased during cancer therapy. When the number of these cells drops below 1000/mm3, it is called neutropenia, which ...Bán 200m² đất tại Thôn 2, Phú Cát, Quốc Oai, Hà Nội. Ngõ thông, đường ô tô đi. Gần chợ, xung quanh kết nối nhiều tiện ích. Gần trường học Phú Cát, ủy ban nhân dân xã Phú …Nursing Interventions. Client Education. anna vanasselberg filgrastim (Neupogren) PHARM Cht leukopoietic growth factor. binds to and stimulates immature neutrophils to divide and differentiate. also activates mature neutrophils. filgrastim interferes with the action of cytotoxic drugs. lithium potentiates release of neutrophils. leukocytosis ...Anemia is a condition where a patient has a below normal level of red blood cells. This can cause symptoms like fatigue, dizziness, weakness and shortness of breath. ….

Now, hematopoietic growth factors act like analogs or synthetic versions of the various physiological growth factors produced by the body. These include granulocyte colony-stimulating factor or G-CSF, granulocyte-macrophage colony-stimulating factor or GM-CSF, thrombopoietin agents, and erythropoietin stimulating agents or ESAs. Let’s start ... Filgrastim is a medication used to manage and treat neutropenia in patients with myelosuppression from chemotherapy or radiation, which increases the risk of infection and related events. This activity outlines the indications, actions, contraindication, adverse effects, and other important details of filgrastim as it pertains to members of the ...Filgrastim injection is used to treat neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in your body called a colony stimulating factor. Filgrastim helps the bone marrow to make new white blood cells. When certain cancer medicines are used to fight ...Study with Quizlet and memorize flashcards containing terms like A nurse is assessing a client with a genetic history of cancer. Which assessment finding requires immediate nursing intervention? A.Blood pressure 140/90 B.Nagging cough with hoarseness C.Nasal congestion for several days D.Muscle tension in the cervical spine, The nurse …Access this comprehensive nursing care plan and management guide to deliver optimal care for patients facing challenges in performing self-care and activities of daily living. This valuable resource provides a wealth of information on nursing assessments, interventions, goals, and nursing diagnoses specifically designed to …A client is taking G-CSF, or filgrastim (Neupogen). Which nursing interventions are indicated for the most common side effect of this medication? a. Stool softeners and a high-fiber diet for constipation b. High fluid intake and vitamin C for alkaline urine c. Acetaminophen (Tylenol) and assessment for fever d. Nonnarcotic analgesia and comfort ...Notify physician or nursing staff immediately if these reactions occur. Watch for and report signs of leukopenia (fever, sore throat, signs of infection), thrombocytopenia (bruising, nose bleeds, and bleeding gums), or unusual weakness and fatigue that might be due to anemia or other blood dyscrasias. Top 300 - Spring 2024 (P2) 61 terms. liud255. Preview. Respiratory Pharmacology Quiz Chapter 11. 35 terms. briannajane9. Preview. Study with Quizlet and memorize flashcards containing terms like Brand name, Therapeutic class, Pharmacologic class and more. Filgrastim nursing interventions, Are you a nurse looking for ways to make cash? This list of great side hustles for nurses spans nearly all genres of interest and training. Home Make Money Side Hustles If you’re..., Violence in the east African country has claimed hundreds of lives and created fears of "mass violence." Burundi has rejected the decision by the African Union (AU) to send in troo..., Study with Quizlet and memorize flashcards containing terms like A nursing assistant in a nursing home reports to the nurse that an 87-year-old nursing home client has a 6-inch reddened wound with pus draining from it on his shin where he scratched it open yesterday. After directly assessing the client's wound, what are the most relevant priority actions for the nurse to take? Select all that ..., Sep 22, 2017 · Filgrastim’s approval for ARS was based on efficacy studies in animals and filgrastim data from other approved indications . Filgrastim dose, timing, and duration were provided in most studies in CIN [4, 19–21, 23–31], AML [33–38], SCN [6, 40], and BMT [41, 42] but varied across studies (Online Resources 4 and 5). Further evaluation is ... , Nursing Management. There are a couple of nursing management and considerations that nurses have to keep in mind when taking care of a client with leukemia. Radiation and Chemotherapy. These are primarily given to decrease the abnormally high number of white blood cells. Radiation and chemotherapy will technically restart the …, Some of the professionals that work most with helping people with schizophrenia are nurses. There are so many Some of the professionals that work most with helping people with schi..., Study with Quizlet and memorize flashcards containing terms like A nurse is caring for a client with multiple myeloma. Which nursing intervention is most appropriate for this client?, The clinic nurse is caring for a client diagnosed with leukopenia. What does the nurse know this client has?, Which term refers to a form of white blood cell involved in …, Chapter 13 Personal Care Skill. 27 terms. whooligang. Preview. Exam 2 cardiopulm. 46 terms. pjlanham. Preview. KINES 100 Module 1. ... A nurse is preparing to administer filgrastim for the first to a client who has undergone a bone marrow transplant. Which of the following interventions is appropriate? A. Administer IM in a large muscle mass to ..., VIDEO ANSWER: A client is receiving filgrastim (Neupogen). What nursing interventions are appropriate to safely administer this drug and provide client safety throughout therapy Get 5 free video unlocks on our app with code GOMOBILE, This article explores what a registered nurse (RN) does and how you can become one. This article explores how tobecome a nurse Updated May 23, 2023 • 6 min read There's a hard trut..., For this reason, patients are prescribed antibiotics and even receive injections to increase white blood counts (such as filgrastim or lenograstim). If this 0.4 value really pertains to your white counts, then I believe this is really low and what you are experiencing is a condition called 'febrile neutropenia'., Access this comprehensive nursing care plan and management guide to deliver optimal care for patients facing challenges in performing self-care and activities of daily living. This valuable resource provides a wealth of information on nursing assessments, interventions, goals, and nursing diagnoses specifically designed to …, Study with Quizlet and memorize flashcards containing terms like The nurse administers filgrastim (Neupogen) to the client. The nurse explains that this drug is used in the treatment of: a) Acute lymphoblastic leukemia. b) Neutropenia, or neutropenia secondary to chemotherapy. c) Clients with Hodgkin's disease who are having bone marrow …, Filgrastim injection products come as a solution (liquid) in vials and prefilled syringes to be injected subcutaneously (under the skin) or to be slowly or continuously injected intravenously (into a vein). It is usually given once a day, but filgrastim injection products (Neupogen, Nivestym, Releuko, Zarxio) may be given twice a day when it is ..., Recommendations for Filgrastim Use in Adults by Disease Site. Effective Date: June 2016 Updated: August 2018. CCMB Practice Guideline. Clinical Guide. Developed by: Breast, …, The most reliable, and often the only, sign is fever. Teach patients to monitor their temperature and seek medical attention immediately for temperatures of 100.4º F (38º C) or higher. Neutropenic fever, usually defined as a single temperature greater than 100.4º F and an ANC of less than 500/mm3, is a medical emergency., VIDEO ANSWER: A client is receiving filgrastim (Neupogen). What nursing interventions are appropriate to safely administer this drug and provide client safety throughout therapy Get 5 free video unlocks on our app with code GOMOBILE, This activity outlines the indications, actions, contraindication, adverse effects, and other important details of filgrastim as it pertains to …, The most common side effect of Neupogen ® is mild to moderate bone pain. Other possible side effects of Neupogen ® include fever, diarrhea, skin rash and weakness. Enlargement and rupture of the spleen can rarely occur in patients who are receiving Neupogen ®. Patients who develop abdominal pain, particularly in the left side, while ..., The most reliable, and often the only, sign is fever. Teach patients to monitor their temperature and seek medical attention immediately for temperatures of 100.4º F (38º C) or higher. Neutropenic fever, usually defined as a single temperature greater than 100.4º F and an ANC of less than 500/mm3, is a medical emergency., A patient information leaflet for filgrastim will be provided with your take home medication. This will provide you with additional information regarding your filgrastim injections. Useful contact details. Oncology/Haematology Pharmacists -Telephone 01438 284712 or 01438 285394 Email: [email protected]. Granulocyte., Find information on Filgrastim (Granix, Neupogen) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF., A client is taking G-CSF, or filgrastim (Neupogen). Which nursing interventions are indicated for the most common side effect of this medication? a. Stool softeners and a high-fiber diet for constipation b. High fluid intake and vitamin C for alkaline urine c. Acetaminophen (Tylenol) and assessment for fever d. Nonnarcotic analgesia and comfort ..., NEUPOGEN. ®. is contraindicated in patients with a history of serious allergic reactions to human granulocyte colony-stimulating factors (G-CSFs), such as filgrastim or pegfilgrastim. Splenic Rupture. Splenic rupture, including fatal cases, can occur following the administration of NEUPOGEN. ®., Nursing Interventions. Client Education. anna vanasselberg filgrastim (Neupogren) PHARM Cht leukopoietic growth factor. binds to and stimulates immature neutrophils to divide and differentiate. also activates mature neutrophils. filgrastim interferes with the action of cytotoxic drugs. lithium potentiates release of neutrophils. leukocytosis ..., Dec 3, 2019 · Pegfilgrastim (or biosimilar) is administered 24 to 72 hours after the last dose of myelosuppressive chemotherapy during each of the 8 intensive treatment courses. If patients are unable to receive the long-acting pegfilgrastim product, daily filgrastim (or biosimilar) can be administered until the absolute neutrophil count is >1000 cells/mm 3 ... , CDC - Blogs - NIOSH Science Blog – Celebrating Nurses - Could there be a more fitting year to honor nurses? As 2020 comes to a close, so does our blog series celebrating the Year o..., The PHQ-9 is a 9-item depression scale; each item is scored 0 to 3, providing a 0 to 27 severity score. Review family patterns of relating and social behaviors. Social interaction is primarily learned within the family of origin. When inadequate patterns are identified, actions for change can be instituted., Top 300 - Spring 2024 (P2) 61 terms. liud255. Preview. Respiratory Pharmacology Quiz Chapter 11. 35 terms. briannajane9. Preview. Study with Quizlet and memorize flashcards containing terms like Brand name, Therapeutic class, Pharmacologic class and more. , There is an incidence rate of 24.6 cases per 1000 persons for cellulitis. In a large epidemiologic study about skin, soft tissue, joint and bone infections, 37.3% of patients were identified as having cellulitis. There are 32.1 to 48.1 visits per 1000 population for skin and soft tissue infections. Visits for abscess and cellulitis increased ..., Nursing Diagnosis. Based on the data gathered, the nursing diagnoses appropriate for the patient with asthma include: Ineffective airway clearance related to increased production of mucus and bronchospasm. Impaired gas exchange related to altered delivery of inspired O2. Anxiety related to perceived threat of death., Considering these new recommendations during the pandemic and the general trend toward value-based care in oncology, we compared the different CSF prophylaxis strategies from a clinical and economic perspective by assessing the cost-effectiveness of PP versus SP using a biosimilar filgrastim (specifically filgrastim-sndz) in patients with ..., Filgrastim begins to work as soon as it can bind with its receptor sites. Absorption and excretion occur through the kidneys; the elimination half-life is about 3.5 hours. Pharmacodynamics. Filgrastim is produced by E.Coli bacteria that have had the human G-CSF gene inserted. G-CSF regulates the production of neutrophils within the bone marrow.